Description of the Nephrology Training Program University of Iowa College of Medicine

A home hemodialysis patient with abnormal thyroid function tests and hyperprolactinemia is presented. Abnormal thyroid tests included low total triiodothyronine and low total thyroxine and free thyroxine; the latter was documented by the use of both RIA and direct dialysis equilibrium techniques. Serum thyroidstimulating hormone was normal, and the thyroidReceived May 19, 1993. Accepted August 5. 1993. 2 Correspondence to Dr. VS. urn, Division of Nephroiogy. Department of internal Medicine, W336-16, University of Iowa Hospitals, Iowa City, IA 52242. 1046-6673/04 1 0-1 754$03.00/0 Journal of the American Society of Nephrology Copyright C 1994 by the American Society of Nephrology stimulating hormone response to thyrotropin-releasing hormone stimulation was in the low-normal range. Serum prolactin was elevated to more than twice the normal level, and the prolactin response to thyrotropin-releasing hormone was also blunted. The interpretation, pathogenesis, physiologic significance, and management of these abnormalities are discussed.